The Epilepsy Risk Awareness (ERA) Scale: A New Era for Holistic Risk Assessment in Epilepsy

Development of the Epilepsy Risk Awareness scale (ERA scale) for people with epilepsy

PURPOSE Quality of life in people with epilepsy depends on balancing protection from risks and avoiding unnecessary restrictions. The Epilepsy Risk Awareness Checklist (ERAC) was developed to summarise an individual's safety, health care and quality of life and to facilitate communication between professionals. Although effective, the existing Checklist required quantification and shortening to...

Risk assessment in the genomic era.

The sequencing of the human and mouse genomes, and soon that of the rat, offers a foundation to evaluate biological phenomena, including toxicologic effects. Numerous tools are being developed to evaluate aspects of biology based on the DNA sequence. These tools can be utilized to evaluate absorption, distribution, metabolism and excretion, and effects of the toxicologically active product on t...

A new "era of risk-sharing".

Noninvasive surgery for epilepsy: the era of image guidance.

Epilepsy affects approximately 1% to 2% of the US population. It is a family of conditions that, if left untreated, results in recurrent seizures. The underlying disease processes resulting in epilepsy are myriad, and include destructive lesions of the brain, congenital malformations and dysplasias, neoplasms, vascular malformations, medial temporal sclerosis, and metabolic lesions. Fortunately...

TSCA 2.0: A New Era in Chemical Risk Management

After decades of dysfunction, the Toxic Substances Control Act has been overhauled with provisions that promise better protection against potentially harmful chemicals.